People


Publications


Beyond Vision and Eye Movements



Mickey Goldberg's Lab

We study the psychophysics and physiology of cognitive processes in the monkey, using single unit recording, iontophoresis, and careful behavioral measurements. Current projects include elucidation of role of the oculomotor proprioceptive area in monkey somatosensory cortex in the genesis of parietal gain fields; the role of acetylcholine and its antagonists in modulating the activity of neurons in LIP, long-term spatial memory in LIP, and the role of the cerebellum in visuomotor association. Recent discoveries in the laboratory include the demonstration of a spatially untuned signal in the baseline activity of LIP neurons that predicts the monkey's probability of success in a difficult search task, correlates with the neuron's response to the onset of the search array, and inversely with the monkey's recent history of success in the task; the time course of gain fields renders it unlikely that they can be used to specify the spatial location of an object that appeared with 150ms of a prior saccade; and the fact that planning a saccade to the surround of a neuron in LIP suppress the response to a distractor in the neuron's center, and decreases the variability of the response to a distractor in a manner partially independent of firing rate.


Mickey is former President of the Society for Neuroscience

AFFILIATIONS

Columbia University Medical Center

Mahoney-Keck Center for Brain and Behavior Research

Zuckerman Mind Brain Behavior Institute

Kavli Institute for Neuroscience

Department of Neuroscience

Department of Neurology

Department of Psychiatry

Department of Ophthalmology

People


Michael E. Goldberg

• David Mahoney Professor of Brain & Behavior,
  Neuroscience, Neurology, Psychiatry, Ophthalmology;
• Director, Mahoney Center;
• Former President, Society for Neuroscience

meg2008 [at] cumc [dot] columbia [dot] edu
646-774-7389
mailing address:

Michael E. Goldberg, M.D.
Department of Neuroscience
Columbia University
1051 Riverside Drive, Unit 87
Kolb Annex, Room 561
New York, NY 10032
CURRENT SCIENTISTS
STAFF

Anna Ipata
Postdoctoral Fellow

ai2019 [at] cumc [dot] columbia [dot] edu


Xiaolan Wang
Postdoctoral Fellow

xw2135 [at] cumc [dot] columbia [dot] edu
212.543.6931 x108


Latoya Palmer
Lab Administrator;
Mahoney Center Administrator

lp2104 [at] columbia [dot] edu
212.543.6931 x100


???????
Lab Technician

??? [at] cumc [dot] columbia [dot] edu
xxx.xxx.xxxx


Glen Duncan
Technical Specialist III

gduncan [at] mahoney [dot] cpmc [dot] columbia [dot] edu
646.774.7356


John Caban
Machinist

jc3032 [at] cumc [dot] columbia [dot] edu
212.305.6745

SCIENTIFIC ALUMNI
  • Ari Blitz
    Assistant Professor of Radiology (Neuroradiology), Johns Hopkins University

  • Cathie Bushnell
    Harold Griffith Professor of Anesthesia and Neurology, McGill University, Canada

  • James Bisley
    Assistant Professor of Neuroscience, UCLA

  • Charlie Bruce
    Associate Professor of Neuroscience, Yale University

  • Carol Colby
    Professor of Neuroscience, University of Pittsburgh

  • Jean-Rene Duhamel
    Director of Research, Institute of Cognitive Science at CNRS, Lyon, France

  • Jay Edelman
    Assistant Professor of Neuroscience, CUNY

  • Ed FitzGibbon
    Investigator, Laboratory of Sensorimotor Research, NEI, NIH

  • Angela Gee
    Science Teaching Fellow, Columbia University

  • Jackie Gottlieb
    Assistant Professor of Neuroscience, Columbia University

  • Ryohei P. Hasegawa
    Investigator, Electro-technical Institute, Tsukuba, Japan
  • Morgan Jeffries
    Resident in Neurology, Columbia University

  • Suresh Krishna
    Research Associate, Institute of Cognitive Science at CNRS, Lyon, France

  • Makoto Kusunoki
    Research Associate, Oxford University

  • Carl Olson
    Professor of Neuroscience, Carnegie Mellon University

  • Keith Powell
    Lily Pharmaceutical

  • Mark Segraves
    Associate Professor of Neuroscience, Northwestern University

  • Marc Umeno
    Microsoft

  • Mark Walker
    Associate Professor of Neurology, Case Western Reserve University

  • Mingsha Zhang
    Investigator, Institute of Neuroscience, Shanghai, China

  • Ari Zivotovsky
    Associate Professor of Neuroscience, Bar-Ilan University, Israel



Publications

RECENT PAPERS

Zhang, M., X. Wang and M. E. Goldberg (2014). "A spatially nonselective baseline signal in parietal cortex reflects the probability of a monkey's success on the current trial." Proc Natl Acad Sci U S A 111(24): 8967-8972.

Krishna BS, Ipata AE, Bisley JW, Gottlieb J, & Goldberg ME (2014) Extrafoveal preview benefit during free-viewing visual search in the monkey. J Vis 14(1).

Falkner AL, Goldberg ME, & Krishna BS (2013) Spatial representation and cognitive modulation of response variability in the LIP priority map. J. Neurosci. 33(41):16117-16130.

Steenrod S, Phillips MH, & Goldberg ME (2013) The lateral intraparietal area (LIP) codes the location of saccade targets and not the dimension of the saccades that will be made to acquire them. J Neurophysiol 109(10):2596-2605.

Xu B, Karachi C, & Goldberg M (2012) The postsaccadic unreliability of gain fields renders it unlikely that the motor system can use them to calculate target position in space. Neuron 76(6):1201-1209.

Ipata, A., A. Gee, et al. (2012). "Feature attention evokes task-specific pattern selectivity in V4 neurons." Proceedings of the National Academy of Sciences of the United States of America 109(42): 16778-16785. PMID: 23043119

Xu Y, Wang X, Peck C, Goldberg, ME. The time course of the tonic oculomotor proprioceptive signal in area 3a of somatosensory cortex. J. Neurophysiology, 106:71-7, 2011.

Gee AL, Ipata AE, Goldberg ME. Activity in V4 reflects the direction, but not the latency, of saccades during visual search. J Neurophysiol. 104: 2187-2193, 2010

Falkner AE, Krishna BS, Goldberg ME. Surround suppression sharpens the priority map in LIP. J. Neurosci, 38:12787-97, 2010.

Bisley JW, Goldberg ME. Attention, intention, and priority in the parietal lobe. Ann. Rev. Neurosci 33:1-21, 2010.

Jeffries SM, Kusunoki M, Bisley JW, Cohen IS, Goldberg ME. (2007). Rhesus monkeys mislocalize saccade targets flashed for 100ms around the time of the saccade. Vision Res, 47, 1924-1934.   [PDF]

Wang X, Zhang M, Cohen IS, Goldberg ME. (2007). The proprioceptive representation of eye position in monkey primary somatosensory cortex. Nat Neurosci, 10, 640-646.   [PDF]


Cover of Nature Neuroscience, Vol 10 (5), associated with Wang et al 2007.

About the cover:   An eye position signal is required by the cortex, but its source has long been unknown. In this issue, Wang and colleagues identify a proprioceptive eye position signal in primate primary somatosensory cortex. The cover is an abstract image inspired by these findings, courtesy of Ellen Levy.


CLASSICS

Duhamel JR, Colby CL, Goldberg ME. (1998). Ventral intraparietal area of the macaque: Congruent visual and somatic response properties. J Neurophysiol, 79, 126-136.   [PDF]

Gottlieb J, Kusunoki M, Goldberg ME. (1998). The representation of visual salience in monkey parietal cortex. Nature, 391, 481-484.   [PDF]

Duhamel JR, Colby CL, Goldberg ME. (1992). The updating of the representation of visual space in parietal cortex by intended eye movements. Science, 255, 90-92.   [PDF]

Duhamel JR, Goldberg ME, Fitzgibbon EJ, Sirigu A, Grafman J. (1992). Saccadic dysmetria in a patient with a right frontoparietal lesion: The importance of corollary discharge for accurate spatial behavior. Brain, 115, 1387-1402.

Goldberg ME, Bruce CJ. (1990). Primate frontal eye fields. III. Maintenance of a spatially accurate saccade signal. J Neurophysiol, 64, 489-508.   [PDF]

Bruce CJ, Goldberg ME. (1985). Primate frontal eye fields: I. Single neurons discharging before saccades. J Neurophysiol, 53, 603-635.   [PDF]

Bushnell MC, Goldberg ME, Robinson DL. (1981). Behavioral enhancement of visual responses in monkey cerebral cortex: I. Modulation in posterior parietal cortex related to selective attention. J Neurophysiol, 46, 755-772.   [PDF]

Goldberg ME, Bushnell MC. (1981). Behavioral enhancement of visual responses in monkey cerebral cortex: II. Modulation in frontal eye fields specifically related to saccades. J Neurophysiol, 46, 773-787.   [PDF]

Goldberg ME, Wurtz RH. (1972). Activity of superior colliculus in behaving monkeys. II. Effect of attention on neuronal responses. J Neurophysiol, 35, 560-574.   [PDF]

Wurtz RH, Goldberg ME. (1971). Superior colliculus cell responses related to eye movement in awake monkeys. Science, 171, 82-84.   [PDF]


REVIEWS

Goldberg ME. (2007). Studying the visual system in awake monkeys: Two classic papers by Robert H. Wurtz. J Neurophysiol, 98, 2495-2496.   [PDF]

Goldberg ME, Bisley JW, Powell KD, Gottlieb J. (2006). Saccades, salience and attention: The role of the lateral intraparietal area in visual behavior. Prog Brain Res, 155, 157-175.   [PDF]

Bisley JW, Goldberg ME. (2003). The role of the parietal cortex in the neural processing of saccadic eye movements. Adv Neurol, 93, 141-157.

Goldberg ME, Bisley J, Powell KD, Gottlieb J, Kusunoki M. (2002). The role of the lateral intraparietal area of the monkey in the generation of saccades and visuospatial attention. Ann N Y Acad Sci, 956, 205-215.   [PDF]

Ross J, Morrone ME, Goldberg ME, Burr DC. (2001). Changes in visual perception at the time of saccades. Trends Neurosci, 24, 113-121.   [PDF]

Colby CL, Goldberg ME. (1999). Space and attention in parietal cortex. Annu Rev Neurosci, 22, 319-349.   [PDF]



Beyond Vision and Eye Movements

  • Arts and entertainment



Brooklyn Academy of Music


Dance Theater Workshop


Danspace Project




Joyce Theater Foundation


La Mama Experimental Theatre Club


The Metropolitan Museum of Art




The Metropolitan Opera


New York Theatre


New York Theatre Workshop




Performance Space 122


Whitney Museum of American Art


Gateway National Recreation Area




Burning Man


Open Source Shakespeare


William James



  • Grandchildren



Bronwyn Patience Biernat Goldberg


Shoshana Yehudit Goldberg

Last updated 11/26/08.